Duilio Marchesini was born in Rome.
Achille Funi, Guido Ballo, Domenico Purificato, Giuseppe Capogrossi, Brancaccio, Gigotti, Montanarini e Virgilio Guzzi were his teachers; he attended the Academy of Fine Arts, first in Naples then in Brera (Milan); he was a teacher of Artistic Subjects in secondary school and still give lessons of Drawing, History of Art and Pictorial Techniques.

He attended many art exhibitions in Rome and his works are in private collections and cultural or religious organizations, because he is particularly skilled in portraits and compositions on religious topics.

The painter supports, with pictorial works and critical essays, the logical continuity of artistic figuration, deeply persuaded that human being could always change without denying his soul-body structure, i. e. corporeal matter enlivened by a spiritual principle.

His research in the pictorial field consists in giving an impression of up-to-date modernity to the figurative tradition, this arguing openly with all who mean to express human matters with graphics and paintings separated from tangible reality.